Metofluthrin is a pyrethroid used as an insect repellent. The vapors of metofluthrin are highly effective and capable of repelling up 97% of mosquitoes in field tests. Metofluthrin is used in a variety of consumer products, called emanators, for indoor and outdoor use. These products produce a vapor that protects an individual or area; however, metofluthrin is not meant to be applied directly to human skin. Although metofluthrin has insectidal properties against other insects, it may not be an effective repellent for insects other than mosquitoes.

On a large scale bifenthrin is often used against red imported fire ants. It is also effective against aphids, worms, ants, gnats, moths, beetles, grasshoppers, mites, midges, spiders, ticks, yellow jackets, maggots, thrips, caterpillars, flies and fleas. It is mostly used in orchards, nurseries and homes. In the agricultural sector, it is used in great amounts on certain crops, like corn. About 70% of all hops and raspberries cultured in the United States are treated with bifenthrin. Bifenthrin is very toxic to many insects, fish and other aquatic animals. It is only slightly toxic to mammals and not at all toxic to plants. Even though it does not have a large toxicological risk towards mammals or birds, bifenthrin is able to accumulate in food, and therefore might be dangerous to mammals or birds in some scenarios.